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Determination Of Oral Glucose Tolerance (ogt) Of Benign Prostatic Hyperplasia Patients Treated With Tamsulosin In Sokoto State, Nigeria

 
  (Vol. 9 Number 2) by 1malami Dikko, 2shaibu Oricha Bello, 2aminu Chika, 3ismaila Arzika Mungadi, 4*yusuf Sarkingobir, 5sulaiman Aliyu  
     
 

This study determined the effect of tamsulosin on blood glucose tolerance among patients of benign prostatic hyperplasia/ lower urinary tract symptoms in Sokoto state, Nigeria. Standard methods were used in this study.The result revealed a significant increase (P<0.05) in the area under oral glucose tolerance test (OGTT) curve at 2nd month,3rd month, and 4thmonth progressively. Comparisons between mean values at other time points were not significantly different (P>0.05). A change (P<0.05) in the total area under the OGTT curve was observed in BPH patients aged 55-64 years at 4th month compared to the values of the 0th and 1st months. Comparisons between mean values at other time points were not significantly different (P>0.05). At 0th or 1stor 2ndor 3rd or 4th month, there was no significant difference (P>0.05) in the total area under the OGTT curve between the three (3) age groups.The results of the study showed that tamsulosin caused hyperglycemiain BPH patients. It is recommended that blood glucose levels in BPH patients using tamsulosin should be monitored to avoid hyperglycemia complications.


Keywords: Tamsulosin, glucose, hyperglycemia, humans, adverse drug reactions


 
     
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