Latest Edition
 

Page Visit Counter
Visitors: 37,477

 

Featured Article:

 

Evaluation Of The Phytochemical Constituents And Antioxidant Activity Of The Stem Of Senecio Biafrae (asteraceae)

 
  (Vol. 6 Number 2) by Oluwatosin O. Johnson*, David K. Adeyemi, Oluwaseun Adeusi And Gloria A. Ayoola  
     
 

The use of herbal products is of global importance because of their low side effects, accessibility and affordability when compared with conventional medicine. The objective of this study was to investigate the phytochemical content and in-vitro antioxidants activities of the methanol extract of Senecio biafrae stem. The methanol extract was obtained by cold maceration method. Phytochemical investigation was carried out using standard procedures. In-vitro anti-oxidant activity was estimated by 2, 2-diphenyl-1-picryl hydrazyl (DPPH) radical scavenging activity and Ferric Reducing Antioxidant Power (FRAP) assay. The qualitative analysis revealed the presence of alkaloids, reducing sugars, cardiac glycosides, steroids, flavonoids and saponins while tannins and anthraquinones were absent in the extracts. The DPPH assay showed percentage inhibition ranging from 40.08±0.26 to 47.27±0.02% for Seneco biafrae stem extract, 96.64±0.07 to 98.76±0.01% for ascorbic acid and 54.62±0.06 to 58.99±0.06% for alpha tocopherol, with IC50 112.58 μg/ml, 5.66 μg/ml and 18.51 μg/ml respectively. The FRAP assay of the extract was 107 μM Fe2+/g dry extract while the positive control (ascorbic acid) had a value of 272.5 μMFe2+/g dry material. This study shows that the methanol extract of Senecio biafrae stem possesses various phytochemical constituents, has antioxidant potential and could be very useful in the prevention and treatment of various diseases and ailments.

Key words: Phytochemicals, Senecio biafrae, Antioxidant, 2, 2-diphenyl-1-picryl hydrazyl (DPPH)


 
     
  PDF ButtonDownload PDF (Right-Click and Click "Save As") (466.83kb)  
     

*You need Adobe Acrobat Reader to view this Document

*If you cannot view or open this document, please download and Install Acrobat Reader via the link below

Adobe Acrobat Reader

 


| Powered by PenielBiz
Home | About | Archive | Pulication Guide | Editorial TeamEnquiries | Admin Login | Email Login